ELLIPSOMETRY, RAMAN SPECTROSCOPY AND SOI- NANOWIRE BIOSENSOR IN DIAGNOSIS OF COLORECTALCANCER

Autor: M. V. Kruchinina, Ya. I. Prudnikova, S. A. Kurilovich, A. A. Gromov, V. N. Kruchinin, V. V. Atuchin, O. V. Naumova, E. V. Spesivtsev, V. A. Volodin, S. E. Peltek, G. V. Shuvalov, V. M. Generalov
Jazyk: ruština
Rok vydání: 2017
Předmět:
Zdroj: Сибирский онкологический журнал, Vol 16, Iss 4, Pp 32-41 (2017)
Druh dokumentu: article
ISSN: 1814-4861
2312-3168
DOI: 10.21294/1814-4861-2017-16-4-32-41
Popis: Differences in the rate constants of specific interactions between serum tumor M2-pyruvate kinase (Tumor M2-PK) and highly specific monoclonal antibodies deposited on the surface of biochips were found in colorectal cancer patients using surface plasmon resonance enhanced ellipsometry. Scanning ellipsometry revealed a significant increase in the biomolecular layer thickness caused by antigen-antibody reaction in patients with hepatic and extra-hepatic metastases compared to that in healthy subjects (p
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