Immunofluorescence Assay for Serologic Diagnosis of SARS

Autor:	Paul K.S. Chan, King-Cheung Ng, Rickjason C. W. Chan, Rebecca K. Y. Lam, Viola C. Y. Chow, Mamie Hui, Alan Wu, Nelson Lee, Florence H.Y. Yap, Frankie W. T. Cheng, Joseph J. Y. Sung, John S. Tam
Jazyk:	angličtina
Rok vydání:	2004
Předmět:	coronavirus diagnosis serology sensitivity specificity severe acute respiratory syndrome Medicine Infectious and parasitic diseases RC109-216
Zdroj:	Emerging Infectious Diseases, Vol 10, Iss 3, Pp 530-532 (2004)
Druh dokumentu:	article
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1003.030493
Popis:	We evaluated a virus-infected cell-based indirect immunofluorescence assay for detecting anti–severe acute respiratory syndrome-associated coronavirus (SARS-CoV) immunoglobulin (Ig) G antibody. All confirmed SARS cases demonstrated seroconversion or fourfold rise in IgG antibody titer; no control was positive. Sensitivity and specificity of this assay were both 100%. Immunofluorescence assay can ascertain the status of SARS-CoV infection.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/8bc1bb45413d4942932748cbe31b6adb Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF