Macrophage accumulation in dorsal root ganglion is associated with neuropathic pain in experimental autoimmune neuritis

Autor: Li Chunrong, Cao Fangzheng, Zhang Houwen, Fan Weijiao, Cheng Yifan, Lou Yao, Wang Yiqi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Translational Neuroscience, Vol 15, Iss 1, Pp 53-60 (2024)
Druh dokumentu: article
ISSN: 2081-6936
DOI: 10.1515/tnsci-2022-0355
Popis: Neuropathic pain is a common symptom of Guillain–Barré syndrome (GBS). The infiltration of macrophages in the dorsal root ganglion (DRG) contributed to neuropathic pain in nerve injury. The underlying mechanisms of neuropathic pain in patients with GBS remain unknown. Experimental autoimmune neuritis (EAN) is a useful mice model of GBS. Our study aimed to explore whether the infiltration of macrophages in DRG is associated with neuropathic pain of EAN.
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