Pyrexia in a young infant – is height of fever associated with serious bacterial infection?

Autor: Tan Shi Rui Victoria, Ong Gene Yong-Kwang, Lee Khai Pin, Ganapathy Sashikumar, Chong Shu-Ling
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Pediatrics, Vol 22, Iss 1, Pp 1-7 (2022)
Druh dokumentu: article
ISSN: 1471-2431
DOI: 10.1186/s12887-022-03264-8
Popis: Abstract Background Febrile infants ≤ 90 days old make up a significant proportion of patients seeking care in the emergency department (ED). These infants are vulnerable to serious bacterial infections (SBIs) and early identification is required to initiate timely investigations and interventions. We aimed to study if height of an infant’s temperature on presentation to the ED is associated with SBI. Methods We performed a retrospective chart review on febrile infants ≤ 90 days old presenting to our ED between 31st March 2015 and 28th February 2016. We compared triage temperature of febrile infants with and without SBIs. We presented sensitivity, specificity, positive and negative predictive values (PPV and NPV) of fever thresholds at triage. A multivariable regression was performed to study the association between height of temperature and the presence of SBI, and presented the adjusted odds ratio (aOR) with corresponding 95% confidence intervals (CI). Results Among 1057 febrile infants analysed, 207 (19.6%) had a SBI. Mean temperature of infants with a SBI was significantly higher than those without (mean 38.5 °C, standard deviation, SD 0.6 vs. 38.3 °C, SD 0.5, p
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