Prevalence of dyslipidemia associated with complications in diabetic patients: a nationwide study in Thailand

Autor: Ploypun Narindrarangkura, William Bosl, Ram Rangsin, Panadda Hatthachote
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Lipids in Health and Disease, Vol 18, Iss 1, Pp 1-8 (2019)
Druh dokumentu: article
ISSN: 1476-511X
DOI: 10.1186/s12944-019-1034-3
Popis: Abstract Background Dyslipidemia is an important modifiable risk factor for cardiovascular disease. It is diagnosed by the presence of an abnormal lipid profile, primarily with elevated levels of plasma cholesterol, triglyceride, or both, or reduced levels of high-density lipoprotein cholesterol. However, some studies have reported increased risk of ischemic stroke with elevated low-density lipoprotein cholesterol (LDL-C) levels and increased risk of cardiovascular mortality independent of LDL-C levels in type 2 diabetes mellitus (T2DM) patients. Methods In this cross-sectional study, data were included for Thai adults with diabetes from the Diabetes Mellitus/ Hypertension (DM/HT) study, 2010–2014 (data was collected by the Medical Research Network of the Consortium of Thai Medical Schools). The target population comprised T2DM patients who were treated at a hospital for more than 12 months. Adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were calculated to determine factors associated with dyslipidemia. Results In total, 140,557 participants (average age, 60 years) were enrolled, with a dyslipidemia prevalence of 88.9% in the cohort. The factors associated with dyslipidemia included female sex (aOR: 1.47, 95% CI: 1.38–1.56); age
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