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Leonard I Voronov,1,2 Krzysztof B Siemionow,3 Robert M Havey,1,2 Gerard Carandang,2 Avinash G Patwardhan1,2 1Department of Orthopaedic Surgery and Rehabilitation, Loyola University Chicago, Maywood, 2Musculoskeletal Biomechanics Laboratory, Edward Hines Jr. VA Hospital, Hines, 3Department of Orthopaedics, University of Illinois College of Medicine at Chicago, Chicago, IL, USA Introduction: Lateral mass screw (LMS) fixation with plates or rods is the current standard procedure for posterior cervical fusion. Recently, implants placed between the facet joints have become available as an alternative to LMS or transfacet screws for patients with cervical spondylotic radiculopathy. The purpose of this study was to evaluate the biomechanical stability of the DTRAX® cervical cage for single- and two-level fusion and compare this to the stability achieved with LMS fixation with rods in a two-level construct.Methods: Seven cadaveric cervical spine (C3–C7) specimens were tested in flexion–extension, lateral bending, and axial rotation to ±1.5 Nm moment without preload (0 N) in the following conditions: 1) intact (C3–C7), 2) LMS and rods at C4–C5 and C5–C6, 3) removal of all rods (LMS retained) and placement of bilateral posterior cages at C5–C6, 4) bilateral posterior cages at C4–C5 and C5–C6 (without LMS and rods), and 5) C4–C5 and C5–C6 bilateral posterior cages at C4–C5 and C5–C6 with rods reinserted.Results: Bilateral posterior cervical cages significantly reduced range of motion in all tested directions in both single- and multilevel constructs (P |