New oral and topical approaches for the treatment of melasma

Autor: P.E. Grimes, MD, S. Ijaz, BA, MPH, R. Nashawati, BS, MSGM, D. Kwak
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Women's Dermatology, Vol 5, Iss 1, Pp 30-36 (2019)
Druh dokumentu: article
ISSN: 2352-6475
DOI: 10.1016/j.ijwd.2018.09.004
Popis: Melasma is a common, therapeutically challenging, and universally relapsing disorder of hyperpigmentation that is most often observed in women and individuals with Fitzpatrick Skin Types III through VI. The pathogenesis of melasma is complex and protean. Contributing factors that are often implicated in the etiopathogenesis of this condition include a genetic predisposition, intense ultraviolet radiation exposure, and hormonal influences. Therapeutic interventions for melasma include a multimodality approach incorporating photoprotection agents, topical and oral skin lighteners, and resurfacing procedures. Given our expanding knowledge of the pathogenesis of melasma, new and effective treatments are expanding our therapeutic armamentarium. This article reviews new and emerging oral and topical treatments for melasma. Keywords: Melasma, photoprotection, lightening agents, oral treatments, topical treatments, new and emerging
Databáze: Directory of Open Access Journals