Free radical production in the smoking of e-cigarettes and their possible effects in human health

Autor: Roberto Menicagli, Ortensio Marotta, Roberta Serra
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: International Journal of Preventive Medicine, Vol 11, Iss 1, Pp 53-53 (2020)
Druh dokumentu: article
ISSN: 2008-7802
2008-8213
DOI: 10.4103/ijpvm.IJPVM_424_19
Popis: Background: The increase in smoking e-cigarettes with nicotine or only flavoring compounds requires a deep study on consequences on human health. This research aims to study the possible process, to form free radicals or the nuclei's damages with consequent micronuclei's formation. Methods: The study analyzed three groups: the first one that uses e-cigarettes with nicotine, (e-nicotine), the second flavoured liquid (e-vapor) and third the not-smoking group. We determinated the salivary malondialdehyde (MDA), the total salivary mucins (SM). and in buccal smear cells the micronuclei (MN). We statistically analyzed the results with the Mann-Whitney U Test Calculator. Results: Smoking e-cigarettes e-nicotine or e-vapor produced a great and significative amount of MDA vs control group: p ≤ 0.05. Only those smoking e-nicotine, have a highest and statically significant amount of salivary mucins vs control group: P value 00496. In both smokers groups, the mean of MN scores has a significant difference vs control group P ≤ 0.05. Conclusions: This study shows the possible damages of the nuclei, but the increase of radicals, oral mucins and MN needs more researches.
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