To date the greenest method for the preparation of α-hydroxyphosphonates from substituted benzaldehydes and dialkyl phosphites
| Autor: | Keglevich György, Rádai Zita, Kiss Nóra Zsuzsa |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Green Processing and Synthesis, Vol 6, Iss 2, Pp 197-201 (2017) |
| Druh dokumentu: | article |
| ISSN: | 2191-9542 2191-9550 |
| DOI: | 10.1515/gps-2016-0125 |
| Popis: | Recent synthetic methods for α-hydroxyphosphonates comprise a green, solvent-free accomplishment of the Pudovik reaction that was typically followed by extractions and recrystallization, or even by chromatography, or other operations. We now developed a general procedure applying 10% of triethylamine as the catalyst and a minimum quantity of acetone as the solvent, giving the products in a pure form after a reflux of 5–120 min following the addition of some n-pentane and crystallization on cooling. |
| Databáze: | Directory of Open Access Journals |
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