Neurosyphilis: An Unresolved Case of Meningitis

Autor: Shagufta Ahsan, Joesph Burrascano
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Case Reports in Infectious Diseases, Vol 2015 (2015)
Druh dokumentu: article
ISSN: 2090-6625
2090-6633
DOI: 10.1155/2015/634259
Popis: Neurosyphilis can cause both symptomatic and asymptomatic meningitis. However the epidemiology of modern neurosyphilis is not well defined because of the paucity of population-based data. The majority of neurosyphilis cases have been reported in HIV-infected patients. Here we present a case of early neurosyphilis/symptomatic syphilitic meningitis in a non-HIV patient who presented with rash but was mistakenly treated for early latent or secondary syphilis. Syphilis presenting with a skin rash and an extremely high RPR titer could indicate CNS infection rather than simply secondary syphilis because rash is a nonspecific manifestation of disseminated infection. Given the effectiveness of penicillin therapy, why is the rate of syphilis continuing to increase? Is it due to a failure of prevention or could it be also because of failure to diagnose and treat syphilis adequately, as in this case?
Databáze: Directory of Open Access Journals