| Autor: |
Maria Antonella Zingaropoli, Parni Nijhawan, Anna Carraro, Patrizia Pasculli, Paola Zuccalà, Valentina Perri, Raffaella Marocco, Blerta Kertusha, Guido Siccardi, Cosmo Del Borgo, Ambrogio Curtolo, Camilla Ajassa, Marco Iannetta, Maria Rosa Ciardi, Claudio Maria Mastroianni, Miriam Lichtner |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Frontiers in Immunology, Vol 12 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1664-3224 |
| DOI: |
10.3389/fimmu.2021.627548 |
| Popis: |
BackgroundEmerging evidence argues that monocytes, circulating innate immune cells, are principal players in COVID-19 pneumonia. The study aimed to investigate the role of soluble (s)CD163 and sCD14 plasmatic levels in predicting disease severity and characterize peripheral blood monocytes and dendritic cells (DCs), in patients with COVID-19 pneumonia (COVID-19 subjects).MethodsOn admission, in COVID-19 subjects sCD163 and sCD14 plasmatic levels, and peripheral blood monocyte and DC subsets were compared to healthy donors (HDs). According to clinical outcome, COVID-19 subjects were divided into ARDS and non-ARDS groups.ResultsCompared to HDs, COVID-19 subjects showed higher sCD163 (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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