Patterns of National Cancer Institute‐Sponsored Clinical Trial Enrollment in Black Adolescents and Young Adults

Autor: Michael Roth, Melissa Beauchemin, Justine M. Kahn, Archie Bleyer
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Cancer Medicine, Vol 10, Iss 21, Pp 7620-7628 (2021)
Druh dokumentu: article
ISSN: 2045-7634
DOI: 10.1002/cam4.4292
Popis: Abstract Background Both adolescent and young adult (AYA) and Black or African American (hereafter referred to as Black) cancer patients are historically under‐enrolled in cancer treatment trials (CTT). The purpose of this study was to quantify enrollment of Black AYAs in National Cancer Institute (NCI)‐sponsored CTTs overall and by age, sex, and cancer diagnosis during 2000–2015. Methods Utilizing data from NCI’s Cancer Therapy Evaluation Program and the Surveillance, Epidemiology and End Results (SEER) Program, we assessed CTT enrollment in Black patients with cancer and measured changes in enrollment over time between the study periods 2000–2007 and 2008–2015. Enrollment patterns were compared across age groups (≤14 years [y], 15–19y, 20–29y, 30–39y and 40+ years), sex, and cancer diagnosis. Results From 2000 through 2015,
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