Contribution of Streptococcus anginosus to Infections Caused by Groups C and G Streptococci, Southern India

Autor: Silvana Reißmann, Claudia Friedrichs, Reena Rajkumari, Andreas Itzek, Marcus Fulde, Arne C. Rodloff, Kootallur N. Brahmadathan, Gursharan S. Chhatwal, D. Patric Nitsche-Schmitz
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 16, Iss 4, Pp 656-663 (2010)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid1604.090448
Popis: Vellore, a region in southern India, has a high incidence of severe human infections with β-hemolytic group C and G streptococci (GCGS). To determine the causative species in these infections, we conducted 16S rRNA gene sequencing: Streptococcus dysgalactiae subsp. equisimilis (81%) and S. anginosus (19%) were the causative organisms in the 2-year study period (2006–2007). We used PCR to detect the virulence-related emm gene; results showed that it was restricted to S. dysgalactieae subsp. equisimilis isolates of 99.2% tested positive. Due to a novel marker, S. anginosus and S. constellatus can be quickly and accurately distinguished from other members of the genus. The notable contribution of the anginosus group to human infections suggests that this group of obligate pathogens deserves more attention in healthcare and research.
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