CARVEDILOL EFFECTS ON INSULIN RESISTANCE AS A FACTOR DEFINING CLINICAL EFFECTIVENESS IN METABOLIC SYNDROME

Autor: V. E. Oleynikov, I. B. Matrosova, I. V. Eliseeva, Yu. A. Tomashevskaya
Jazyk: ruština
Rok vydání: 2009
Předmět:
Zdroj: Российский кардиологический журнал, Vol 0, Iss 2, Pp 59-64 (2009)
Druh dokumentu: article
ISSN: 1560-4071
2618-7620
Popis: In 62 patients with Stage I-II arterial hypertension (AH) and metabolic syndrome (MS), clinical effectiveness and insulin resistance (IR) effects of a non-selective alpha-beta-adrenoblocker carvetrend were investigated, for 16-week carvetrend monotherapy, carvetrend combination with corinfar UNO, or their combination with formin and zorstat. Carvetrend, as monotherapy or combined with corinfar UNO, effectively reduced office and 24-hour monitoring blood pressure levels, regardless of the risk factor number. Carvetrend increased peripheral tissue insulin sensitivity, without affecting carbohydrate and lipid metabolism.
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