Characteristics of Meningitis in Febrile Infants Aged ≤90 Days

Autor: Kyu Un Cho, Su Jeong You
Jazyk: English<br />Korean
Rok vydání: 2021
Předmět:
Zdroj: Annals of Child Neurology, Vol 29, Iss 2, Pp 83-90 (2021)
Druh dokumentu: article
ISSN: 2635-909X
2635-9103
DOI: 10.26815/acn.2020.00318
Popis: Purpose This study evaluated the clinical and laboratory characteristics of infants ≤90 days old with meningitis who presented to the hospital with a fever. We also investigated whether initial C-reactive protein levels and white blood cell counts were reliable predictors of bacterial meningitis. Methods The medical records of 1,151 infants aged ≤90 days who visited our hospital with a fever between October 2009 and October 2019 were retrospectively evaluated. Results Of the 1,151 patients, 274 (23.8%) had meningitis (bacterial, n=7; viral, n=206; pleocytosis in the cerebrospinal fluid, n=136). Thirty-seven viral meningitis patients (18.0%) had a positive polymerase chain reaction result without pleocytosis in the cerebrospinal fluid. The patients without pleocytosis were significantly younger. Among the patients with only pleocytosis, 46 had a urinary tract infection, 22 had other viral infections, and the etiology was unknown in 68. Among patients with urinary tract infections, infants without pleocytosis were younger than those with pleocytosis. Low white blood cell counts (
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