CYTOKINES AND HISTOPATHOLOGIC PATTERN OF MALIGNANT NEOPLASMS IN GASTROINTESTINAL CANCER

Autor: A. I. Autenshluss, A. V. Sosnina, E. S. Mikhailova, D. V. Morozov, N. A. Varaksin, M. Yu. Rukavishnikov, Yu. N. Kozlova, A. V. Kan’shina
Jazyk: ruština
Rok vydání: 2014
Předmět:
Zdroj: Медицинская иммунология, Vol 11, Iss 1, Pp 29-34 (2014)
Druh dokumentu: article
ISSN: 1563-0625
2313-741X
DOI: 10.15789/1563-0625-2009-1-29-34
Popis: The patients with gastrointestinal cancer exhibit high contents of TNFα, IL-1β, IL-2, IL-6, IL-8, IFNγ, IL-1Ra and increased levels of anti-IFNα antibodies. Significant correlations are detected between histopathological parameters of the tumors, and the levels of TNFα, IL-2, IL-6, IL-8, IFNα, IFNγ, as well as antibodies against TNFα и IFNα. Moreover, we have determined diagnostically significant levels of cytokines and their combinations. On the basis of estimated diagnostic values, one may evaluate both current status of the tumor, as well as its potential malignancy grade.
Databáze: Directory of Open Access Journals