Candida species isolated from clinical samples in a tertiary hospital in Honduras: Where is Candida auris?
| Autor: | Bryan Ortiz, Kateryn Aguilar, Celeste Galindo-Morales, Lizzy Molina, Gustavo Fontecha |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Current Medical Mycology, Vol 8, Iss 3, Pp 1-8 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2423-3439 2423-3420 |
| DOI: | 10.18502/cmm.8.3.11212 |
| Popis: | Background and Purpose: Infections by emerging and multiresistant Candida species are becoming more frequent throughout the world. This study aimed to describe Candida species in different wards of a tertiary hospital in Honduras. Materials and Methods: Prevalence of species within the C. albicans complex was estimated using a molecular approach, and C. auris was investigated using a yeast pool-based DNA extraction method. Three hundred and twenty-eight yeast isolates were identified using phenotypic approaches. For identification of species within the albicans complex, a molecular approach based on the size polymorphisms of the hpw1 gene was used. In addition, we optimized a technique based on DNA extraction in pools for the rapid identification of C. auris. Results: Eleven species of Candida were identified in the hospital wards. Candida albicans showed the highest number of isolates (52.4%). Within the Candida albicans complex, C. albicans sensu stricto was the most common followed by C. dubliniensis. C. auris was not found. Conclusion: Reports on the distribution of Candida species in Honduras are limited, thus the data from this study are of importance for a better understanding of their epidemiology. Also, we offer a simple method for the detection of C. auris that could help in its detection in low-resource settings. |
| Databáze: | Directory of Open Access Journals |
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