| Autor: |
Kaoutar Achehboune, Hanane Baybay, Sara Elloudi, Fatima Zahra Mernissi |
| Jazyk: |
English<br />French |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
PAMJ Clinical Medicine, Vol 2, Iss 145 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2707-2797 |
| DOI: |
10.11604/pamj-cm.2020.2.145.22312 |
| Popis: |
Mal de Meleda (MdM) is an autosomal recessive form of palmoplantar keratoderma, that is characterized by transgradient keratoderma with associated scleroatrophy, nail changes, pseudoainhum around digits and perioral erythema, without a tendency for spontaneous resolution. Mal de Meleda can lead to severe flexion contractures in some patients as well as mycotic over-rinfections with significant impact on quality of life and daily activity. Mal de Meleda is a rare genetic disorder but no standardized treatment has been established. Treatment options for this disease include topical keratolytic agents, propylene glycol, topical 5-fluorouracil and surgical treatment. In addition, it has been reported that etretinate and acitretin, usually produce improvement. Herein, we present a case of Mal de Meleda with lips involvement which showed significant clinical improvement with acitritin. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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