Early-Stage Renal Cell Carcinoma Locoregional Therapies: Current Approaches and Future Directions

Autor: Umang Khandpur, Bereket Haile, Mina S Makary
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Clinical Medicine Insights: Oncology, Vol 18 (2024)
Druh dokumentu: article
ISSN: 1179-5549
11795549
DOI: 10.1177/11795549241285390
Popis: Renal cell carcinoma (RCC) is the most common primary renal malignancy. Prevalence of RCC in developed countries has slowly increased. Although partial or total nephrectomy has been the first-line treatment for early-stage RCC, improved or similar safety and treatment outcomes with locoregional therapies have challenged this paradigm. In this review, we explore locoregional techniques for early-stage RCC, including radiofrequency ablation, cryoablation, and microwave ablation with a focus on procedural technique, patient selection, and safety/treatment outcomes. Furthermore, we discuss future advances and novel techniques, including radiomics, combination therapy, high-intensity focused ultrasound, and catheter-directed techniques.
Databáze: Directory of Open Access Journals