Impact of pretreatment anemia on upfront abiraterone acetate therapy for metastatic hormone-sensitive prostate cancer: a multicenter retrospective study

Autor: Teppei Okamoto, Daisuke Noro, Shingo Hatakeyama, Shintaro Narita, Koji Mitsuzuka, Toshihiko Sakurai, Sadafumi Kawamura, Senji Hoshi, Jiro Shimoda, Toshikazu Tanaka, Toshiaki Kawaguchi, Shigeto Ishidoya, Akihiro Ito, Norihiko Tsuchiya, Tomonori Habuchi, Chikara Ohyama
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Cancer, Vol 21, Iss 1, Pp 1-8 (2021)
Druh dokumentu: article
ISSN: 1471-2407
DOI: 10.1186/s12885-021-08206-8
Popis: Abstract Background Anemia has been a known prognostic factor in metastatic hormone-sensitive prostate cancer (mHSPC). We therefore examined the effect of anemia on the efficacy of upfront abiraterone acetate (ABI) in patients with mHSPC. Methods We retrospectively evaluated 66 mHSPC patients with high tumor burden who received upfront ABI between 2018 and 2020 (upfront ABI group). We divided these patients into two groups: the anemia-ABI group (hemoglobin
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