Not too much, not too little. Titrating flow rate to minimise inspiratory effort during helmet CPAP: A bench study
| Autor: | Andrea Coppadoro, Rosa Fracchia, Alice Nova, Andrea Restivo, Alberto Lucchini, Giacomo Bellani, Emanuele Rezoagli, Giuseppe Foti |
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| Jazyk: | angličtina |
| Rok vydání: | 2025 |
| Předmět: | |
| Zdroj: | Pulmonology, Vol 31, Iss 1 (2025) |
| Druh dokumentu: | article |
| ISSN: | 2531-0429 2531-0437 25310429 |
| DOI: | 10.1080/25310429.2024.2411804 |
| Popis: | Background Non-invasive helmet respiratory support is suitable for several clinical conditions. Continuous-flow helmet CPAP systems equipped with HEPA filters have become popular during the recent Coronavirus pandemic. However, HEPA filters generate an overpressure above the set PEEP. Methods A lung simulator was used to mimic patient respiratory mechanics and effort. Compared to room air spontaneous breathing, the additional inspiratory effort attributable to helmet CPAP (ΔPmusHelmet) was recorded at different continuous-flow rates (30-150 L/min), PEEP levels (5, 10, 12.5 cmH2O) and respiratory rates (15, 20, 25, 30 breaths/minute), both with and without a HEPA filter at the outlet port. Results Helmet pressure swings during inspiration largely explained ΔPmusHelmet variations (p70%) at a 90 L/min flow rate. Higher ΔPmusHelmet levels were recorded when the continuous-flow was lower than the peak inspiratory flow (3.7 [3.1; 5.6] cmH2O, p |
| Databáze: | Directory of Open Access Journals |
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