Insulin-like growth factor 1 and sex hormones for assessment of anthropometric and pubertal growth of Egyptian children and adolescents with type 1 diabetes mellitus (single center study)

Autor: Rasha A. Thabet, Eman M. Sherif, Ahmed O Abd ElAal, Rana A. Mahmoud
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Endocrine Disorders, Vol 24, Iss 1, Pp 1-11 (2024)
Druh dokumentu: article
ISSN: 1472-6823
DOI: 10.1186/s12902-024-01596-3
Popis: Abstract Background This study aimed to assess the anthropometric measures and pubertal growth of children and adolescents with Type 1 diabetes mellitus (T1DM) and to detect risk determinants affecting these measures and their link to glycemic control. Patients and methods Two hundred children and adolescents were assessed using anthropometric measurements. Those with short stature were further evaluated using insulin-like growth factor 1 (IGF-1), bone age, and thyroid profile, while those with delayed puberty were evaluated using sex hormones and pituitary gonadotropins assay. Results We found that 12.5% of our patients were short (height SDS 8.2, and albumin/creatinine ratio > 8 (p
Databáze: Directory of Open Access Journals
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