Prenatal Invasive Diagnosis with Quantitative Fluorescent PCR
| Autor: | V. V. Avrutskaja, N. V. Kriventsova, R. A. Shokarev, V. S. Gimbut, S. Y. Kriger |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Медицинский вестник Юга России, Vol 0, Iss 2, Pp 60-62 (2011) |
| Druh dokumentu: | article |
| ISSN: | 2219-8075 2618-7876 |
| Popis: | Purpose: To develop the method of prenatal invasive diagnosis and compare it abilities with traditional genetic cytological examination.Materials and Methods: There was conducted prenatal fetal invasive diagnosis of 366 pregnant women. Depending on the pregnancy age and genetic indications the chorionic villus sampling, cordocentesis and amniocentesis were carried.Results: The obtained samples was treated with QF-PCR and it results was verified by standard karyotyping. In all cases, the differences of the two methods was not observed.Summary: It was shown the technique of quantitative fluorescent polymerase chain reaction (QF-PCR) has advantages over the standard cytologic examination and reduces analysis duration and increases the number of patients. |
| Databáze: | Directory of Open Access Journals |
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