End-condition for solution small angle X-ray scattering measurements by kernel density estimation
Autor: | Hiroshi Sekiguchi, Noboru Ohta, Hideaki Ishibashi, Hideitsu Hino, Masaichiro Mizumaki |
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Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Science and Technology of Advanced Materials: Methods, Vol 2, Iss 1, Pp 426-434 (2022) |
Druh dokumentu: | article |
ISSN: | 2766-0400 27660400 |
DOI: | 10.1080/27660400.2022.2140021 |
Popis: | We develop a method for calculating the minimum X-ray exposure time for X-ray solution scattering experiments using statistical and mathematical approaches to enhance the measurement efficiency while maintaining data quality. Experts can determine the X-ray exposure time for samples by investigating time-series data of scattering profiles and considering the quality of scattering profiles and the samples’ X-ray damage. In this study, we apply a statistical inequality to estimate the kernel density estimation method’s error to determine the minimum X-ray exposure time for protein solution scattering experiments and evaluate the method’s validity using the results of Guinier analysis as an indicator. |
Databáze: | Directory of Open Access Journals |
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