CD147 expression as a clinicopathological and prognostic indicator in breast cancer: a meta-analysis and bioinformatics analysis

Autor:	Shuai Shi, Hong-Yan Ma, Yin-zhou Sang, Ying-bo Ju, Xing-guang Wang, Zhi-Gang Zhang
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	CD147 Breast cancer Prognostic Meta analysis Bioinformatic analysis Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Druh dokumentu:	article
ISSN:	1471-2407
DOI:	10.1186/s12885-024-13202-9
Popis:	Abstract Background CD147 belongs to the immunoglobulin superfamily, also known as Basigin (BSG), and is a highly glycosylated single transmembrane glycoprotein present in various tissues. Meta and bioinformatic analyses were used to explore the correlation between CD147 expression and the clinicopathological characteristics prognosis of breast cancer. Method Literature related to breast cancer was retrieved through PubMed and CNKI databases, and a meta-analysis was conducted using Review Manager 5.2 software. Results The meta-analysis revealed that all articles included data on 522 patients with breast cancer and 492 normal tissues. CD147 expression in breast cancer tissue was higher compared to that in normal tissue([8.92–139.52]; p
Databáze:	Directory of Open Access Journals
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