Intraoperative Post-parathyroidectomy Correlation of PTH Hormone Values with Preoperative Scintigraphy
| Autor: | Iulian SLAVU, Cornelia NITIPIR, Cristina ORLOV-SLAVU, Alexandru DOGARU, Raluca TULIN, Constantin OPRESCU, Adrian TULIN |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Modern Medicine, Vol 30, Iss 2, Pp 95-99 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1223-0472 2360-2473 |
| DOI: | 10.31689/rmm.2023.30.2.95 |
| Popis: | Preoperative parathyroid evaluation through nuclear medicine and intraoperative hormone monitoring has significantly increased the success of the surgical intervention. Material and method: Our study is descriptive, the database is retrospective but it is maintained prospectively. The preoperative protocol included single photon emission computed tomography (SPECT) with the use of technetium-99 sestamibi tracer. We preferred this approach as it allowed 3-D localization of the adenomas. PTH values were obtained from blood drawn from the ipsilateral jugular vein at the regular intervals of 5, 10 and 15 minutes post excision. Results: We had 6 cases with false negative which led to the necessary dissection of the contralateral neck. Two had previous surgery and 4 had tumors in other locations which were observed after the surgical intervention through methodical investigations. We encountered 3 patients with false positive results. 2 had intrathyroidal adenomas and 1 was diagnosed with thyroid papillary carcinoma. Causes of a misinterpretation are related to thyroid disease in association with hyperparathyroidism, a history of parathyroid surgery or multiple locations of hyperproductive parathyroid glands. |
| Databáze: | Directory of Open Access Journals |
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