| Autor: |
Leonardo M. Morales-Jaramillo, David Timaran-Montenegro, Yohana Mateo-Camacho, Christian Torres-Ramírez, Karla Fuentes-Badillo, Valeria Morales-Domínguez, Gerardo Punzo-Alcaraz,, Edgar Tapia-Rangel, Gustavo Feria-Arroyo, Lina Parra-Guerrero, Pedro Sáenz-Castillo, Ana Hernández-Rojas, Manuel Falla-Trujillo, Daniel Obando-Bravo, Giovanni Contla-Trejo, Katherine Jácome-Portilla, Alberto Chávez-Sastré, Jovani Govea-Palma, Santiago Carrillo-Álvarez, Julita Orozco-Vázquez, Dulce Bonifacio-Delgadillo |
| Jazyk: |
English<br />Spanish; Castilian |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Anales de Radiología, México, Vol 22, Iss 1 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2604-2053 |
| DOI: |
10.24875/ARM.21000095 |
| Popis: |
Objective: To assess the association between CT-based percentage of pathological lung opacities volume (%PLOV) and the occurrence of adverse outcomes of patients with COVID-19. Methods: An observational, longitudinal, single-center study was performed including patients with COVID-19. CT-based lung segmentation was performed to calculate %PLOV. The primary endpoint was the occurrence of adverse lung event (ALE), defined as ICU admission, the use of mechanical ventilation, or death. Mann-Whitney U test was performed for univariate analysis. Logistic regression analysis was performed to determine independent predictors of critical illness. Results: 138 patients (84 men [61%]) with a mean age of 47.3 years were enrolled. Median %PLOV was 28.64% (interquartile range [IQR], 6.33-47.22%). ALE occurred in 52 patients (38%) with an overall mortality rate of 21% (29 patients). Multivariate analysis demonstrated that %PLOV was an independent predictor of ALE with an Odds ratio of 1.049 (95% confidence interval [CI], 1.014-1.085) (p < 0.01). Furthermore, a %PLOV of 64% demonstrated a 25.5-fold increased risk of ALE with a sensitivity and specificity higher than 75% (p < 0.01). Conclusion: The quantitative evaluation of chest CT impacts the determination of severity of COVID-19 pneumonia on admission. %PLOV was the strongest predictor for the development of ALE in hospitalized patients. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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