Parafoveal vessel changes in primary open-angle glaucoma and normal-tension glaucoma using optical coherence tomography angiography

Autor: Onishi AC, Treister AD, Nesper PL, Fawzi AA, Anchala AR
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Clinical Ophthalmology, Vol Volume 13, Pp 1935-1945 (2019)
Druh dokumentu: article
ISSN: 1177-5483
Popis: Alex C Onishi, Alison D Treister, Peter L Nesper, Amani A Fawzi, Anupama R Anchala Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USACorrespondence: Anupama R AnchalaDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, 645 North Michigan Avenue, Suite 440, Chicago, IL 60611, USATel +1 312 908 8152Fax +1 312 503 8152Email aanchala@nm.orgPurpose: To evaluate parafoveal and peripapillary perfusion in healthy, glaucoma suspect, normal-tension glaucoma, and primary open-angle glaucoma subjects.Patients and methods: This was a retrospective cross-sectional study with optical coherence tomography angiography imaging with RTVue XR Avanti (Optovue, Inc., Fremont, CA) of 56 eyes (14 healthy, 14 glaucoma suspect, 16 normal-tension glaucoma, and 12 primary open-angle glaucoma) at a tertiary academic referral center. Parafoveal and peripapillary superficial vessel density and parafoveal superficial retinal thickness were the main parameters of interest. Area under receiver operating characteristic curves were calculated.Results: There were significant decreases in parafoveal superficial vessel density in primary open-angle (40.06±4.54%, P
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