Longitudinal Analysis of the Intestinal Microbiota in Persistently Stunted Young Children in South India.

Autor: Duy M Dinh, Balamurugan Ramadass, Deepthi Kattula, Rajiv Sarkar, Philip Braunstein, Albert Tai, Christine A Wanke, Soha Hassoun, Anne V Kane, Elena N Naumova, Gagandeep Kang, Honorine D Ward
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: PLoS ONE, Vol 11, Iss 5, p e0155405 (2016)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0155405
Popis: Stunting or reduced linear growth is very prevalent in low-income countries. Recent studies have demonstrated a causal relationship between alterations in the gut microbiome and moderate or severe acute malnutrition in children in these countries. However, there have been no primary longitudinal studies comparing the intestinal microbiota of persistently stunted children to that of non-stunted children in the same community. In this pilot study, we characterized gut microbial community composition and diversity of the fecal microbiota of 10 children with low birth weight and persistent stunting (cases) and 10 children with normal birth weight and no stunting (controls) from a birth cohort every 3 months up to 2 years of age in a slum community in south India. There was an increase in diversity indices (P
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