Autor: |
Tamás Láng, Diána Dimén, Szilvia Oláh, Gina Puska, Arpád Dobolyi |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
iScience, Vol 27, Iss 7, Pp 110296- (2024) |
Druh dokumentu: |
article |
ISSN: |
2589-0042 |
DOI: |
10.1016/j.isci.2024.110296 |
Popis: |
Summary: The medial preoptic area (MPOA) has long been implicated in maternal and male sexual behavior. Modern neuroscience methods have begun to reveal the cellular networks responsible, while also implicating the MPOA in other social behaviors, affiliative social touch, and aggression. The social interactions rely on input from conspecifics whose most important modalities in rodents are olfaction and somatosensation. These inputs bypass the cerebral cortex to reach the MPOA to influence the social function. Hormonal inputs also directly act on MPOA neurons. In turn, the MPOA controls social responses via various projections for reward and motor output. The MPOA thus emerges as one of the major brain centers for instinctive social behavior. While key elements of MPOA circuits have been identified, a synthesis of these new data is now provided for further studies to reveal the mechanisms by which the area controls social interactions. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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