| Autor: |
Alessio Baricich, Marco Battaglia, Margherita B. Borg, Alberto Loro, Paola Morlino, Lucia Cosenza, Michele Bertoni, Alessandro Picelli, Andrea Santamato, Thierry Deltombe |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Journal of Rehabilitation Medicine, Vol 56 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1651-2081 |
| DOI: |
10.2340/jrm.v56.40437 |
| Popis: |
Objective: To compare the effect of rectus femoris diagnostic motor nerve blocks (DNB) with anaesthetics and rectus femoris muscle botulinum toxin (BoNT-A) injection in multiple sclerosis patients with unilateral stiff-knee gait. Design: Prospective observational study Subjects/Patients: Multiple sclerosis patients in stable condition. Methods: Patients underwent evaluation before and 1 hour after the anaesthetic block, and 1 month after the botulinum injection. Assessment included a 10-m walking test, a 6-minute walking test, a timed-up-and-go (TUG) test, and a Baseline Expanded Disability Status Scale (EDSS). Post-DNB and post-BoNT-A satisfaction was measured with the global assessment of efficacy scale. Results: Fourteen patients with unilateral stiff-knee gait due to multiple sclerosis underwent a DNB, among whom 13 received botulinum injections in the rectus femoris muscle after a satisfying test result. Positive post-DNB results correlated with significant functional improvements after BoNT-A. Higher EDSS and longer time from diagnosis correlated with poorer post-DNB and post-BoNT-A absolute outcomes. Conclusion: DNB showed predictive value for BoNT-A outcomes, especially in the case of worse functional status. It effectively predicted endurance and walking speed improvement, while TUG showed greater improvement after botulinum. In cases of uncertain therapeutic benefit, nerve blocks may provide a valuable diagnostic support, particularly in patients with lower functional status. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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