Advances of Fluorescent Nanodiamond Platforms for Intracellular and On-Chip Biosensing
| Autor: | Taisuke Shimada, Yasuyuki Ueda, Yoshinobu Baba, Hiroshi Yukawa |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Biosensors, Vol 14, Iss 7, p 340 (2024) |
| Druh dokumentu: | article |
| ISSN: | 14070340 2079-6374 |
| DOI: | 10.3390/bios14070340 |
| Popis: | Intracellular and extracellular sensing of physical and chemical variables is important for disease diagnosis and the understanding of cellular biology. Optical sensing utilizing fluorescent nanodiamonds (FNDs) is promising for probing intracellular and extracellular variables owing to their biocompatibility, photostability, and sensitivity to physicochemical quantities. Based on the potential of FNDs, we outlined the optical properties, biocompatibility, surface chemistry of FNDs and their applications in intracellular biosensing. This review also introduces biosensing platforms that combine FNDs and lab-on-a-chip approaches to control the extracellular environment and improve sample/reagent handling and sensing performance. |
| Databáze: | Directory of Open Access Journals |
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