Long-term treatment of morphologically verified myocarditis: successes and probable errors. Case report
| Autor: | Olga V. Blagova, Indira N. Alieva, Victoria A. Kulikova, Alexander V. Nedostup, Evgeniya A. Kogan, Vsevolod P. Sedov, Dmitry A. Parfenov, Alexey N. Volovchenko, Natalia D. Sarkisova |
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| Jazyk: | ruština |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Терапевтический архив, Vol 95, Iss 4, Pp 327-334 (2023) |
| Druh dokumentu: | article |
| ISSN: | 0040-3660 2309-5342 00403660 |
| DOI: | 10.26442/00403660.2023.04.202156 |
| Popis: | Diagnosis and treatment of myocarditis can be challenging, including determining indications for heart transplantation. We present a 6-year medical history of a 54 years old patient with severe morphologically verified viral-negative lymphocytic myocarditis and systemic manifestations (onset of hemorrhagic vasculitis) combined with moderate coronary atherosclerosis, which regressed according to repeated coronary angiography. For 5 years, the patient received immunosuppressive therapy with methylprednisolone and azathioprine with a significant improvement. Repeated relapses of atrial fibrillation required correction of basic therapy and plasmapheresis. The disease was complicated by thyrotoxicosis and multi-organ dysfunction; the autopsy showed persistent myocarditis activity. The myocarditis is a chronic condition and requires a review of the treatment strategy at each stage. |
| Databáze: | Directory of Open Access Journals |
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