Early Acute Graft Rejection in a Heart Transplanted Child with Dilated Cardiomyopathy

Autor: Muntean Iolanda, Barmou Asmaa Carla, Sin Anca Ileana, Suciu Horatiu, Togănel Rodica
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Cardiovascular Emergencies, Vol 6, Iss 2, Pp 43-47 (2020)
Druh dokumentu: article
ISSN: 2457-5518
DOI: 10.2478/jce-2020-0007
Popis: Dilated cardiomyopathy (DCM) is the most common type of cardiomyopathy in children. Heart transplantation is considered standard therapy in dilated cardiomyopathy with end-stage heart failure. We present a case of a 15-year-old patient diagnosed with DCM in the neonatal period, who underwent heart transplantation for end-stage heart failure. Despite the use of induction therapy, the endomyocardial biopsy performed at two weeks post-transplant revealed mixed moderate cellular (2R) and humoral (pAMR2) allograft rejection. Aggressive rejection treatment was initiated with good outcome. Besides endomyocardial biopsy, advanced echocardiography can also be a valuable noninvasive tool for rejection assessment.
Databáze: Directory of Open Access Journals