Targeted Literature Review of the Burden of Respiratory Syncytial Infection among High-Risk and Elderly Patients in Asia Pacific Region

Autor: Daisuke Kurai, JoonYoung Song, Yhu-Chering Huang, Zhijun Jie, Petar Atanasov, Xiaobin Jiang, Luis Hernandez-Pastor, Tom Hsun-Wei Huang, SeongBeom Park, KyungHwa Lim, Peter C. Richmond
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Infectious Diseases and Therapy, Vol 12, Iss 3, Pp 807-828 (2023)
Druh dokumentu: article
ISSN: 2193-8229
2193-6382
DOI: 10.1007/s40121-023-00777-2
Popis: Abstract Introduction The burden of respiratory syncytial virus (RSV), which causes acute respiratory illness, is well recognized among the pediatric population but also imposes a significant risk to the elderly (age ≥ 60) and those with underlying comorbidities. The study aimed to review the most recent data on epidemiology and burden (clinical and economic) of RSV in the elderly/high-risk populations in China, Japan, South Korea, Taiwan, and Australia. Methods A targeted review was conducted of English, Japanese, Korean, and Chinese language articles published from 1 January 2010 to 7 October 2020 relevant for the purpose. Results A total of 881 studies were identified, and 41 were included. The median proportion of elderly patients with RSV in all adult patients with acute respiratory infection (ARI) or community acquired pneumonia was 79.78% (71.43–88.12%) in Japan, 48.00% (3.64–80.00%) in China, 41.67% (33.33–50.00%) in Taiwan, 38.61% in Australia, and 28.57% (22.76–33.33%) in South Korea. RSV was associated with a high clinical burden on those patients with comorbidities such as asthma and chronic obstructive pulmonary disease. In China, inpatients with ARI showed a significantly higher rate of RSV-related hospitalization than outpatients (13.22% versus 4.08%, p
Databáze: Directory of Open Access Journals
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