PREDICTIVE FACTORS OF MORBIDITY ASSOCIATED WITH ESOPHAGEAL VARICEAL BLEEDING IN CHILDREN WITH PORTAL HYPERTENSION

Autor: Maria Carolina Feres de Lima Rocha GAMA, Eleonora Druve Tavares FAGUNDES, Thaís Costa Nascentes QUEIROZ, Adriana Teixeira RODRIGUES, Luiza Caroline VIEIRA, Alexandre Rodrigues FERREIRA
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Arquivos de Gastroenterologia, Vol 60, Iss 2, Pp 247-256 (2023)
Druh dokumentu: article
ISSN: 1678-4219
0004-2803
DOI: 10.1590/s0004-2803.202302023-37
Popis: ABSTRACT Background: Most data on the natural history of portal hypertension come from studies in adults. The morbidity rate of upper gastrointestinal bleeding (UGIB) in children with portal hypertension has not been systematically characterized. Objective: To describe the morbidity and mortality of UGIB in pediatric patients with portal hypertension and identify predictive factors for the occurrence of its main complications. Methods: This retrospective study included pediatric patients with cirrhotic portal hypertension or with extrahepatic portal vein obstruction (EHPVO). Mortality and UGIB complications within a period of up to 6 weeks of the bleeding were investigated. To determine the predictive factors of morbidity, a multivariate analysis was performed using logistic regression; all results were considered significant at P
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