| Autor: |
Chuanbo Sun, Nuo Zhang, Guangpei Xu, Ping Jiang, Shiping Huang, Qun Zhao, Yanfei He |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Journal of Functional Foods, Vol 94, Iss , Pp 105105- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1756-4646 |
| DOI: |
10.1016/j.jff.2022.105105 |
| Popis: |
This study aims to explore the structural features and anti-tumor and immunomodulation activity of polysaccharides from Dendrobium officinale that were prepared using DEAE Sephadex A-50 and Sephadex G100. DOP structure was characterized using colorimetry, HPGPC, GC–MS, FT-IR, and NMR. The molecular weight of DOP was 1.89 × 105 Da. And the DOP consisted of D-mannose, D-glucose, and D-galactose in a mole ratio of 3:2:1. DOP could inhibit the growth of S180 tumors by promoting splenocytes proliferation, enhancing NK cell and CTL activity, and increasing the non-specific and tumor antigen-specific antibody levels. These findings suggested that DOP might be a potential antitumor agent with immunomodulatory activity. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
Full Text from ScienceDirect