Cutting the cost of South African antiretroviral therapy using newer, safer drugs

Autor: W F Venter, B Kaiser, Y Pillay, F Conradie, G B Gomez, P Clayden, M Matsolo, C Amole, L Rutter, F Abdullah, E J Abrams, C P Casas, M Barnhart, A Pillay, A Pozniak, A Hill, L Fairlie, M Boffito, M Moorhouse, M Chersich, C Serenata, J Quevedo, G Loots
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: South African Medical Journal, Vol 107, Iss 1, Pp 28-30 (2017)
Druh dokumentu: article
ISSN: 0256-9574
2078-5135
Popis: Antiretrovirals are a significant cost driver for HIV programmes. Current first-line regimens have performed well in real-life programmes, but have a low barrier to virological resistance and still carry toxicity that limits adherence. New drug developments may mean that we have access to safer, more robust and cheaper regimens, but only if the appropriate clinical trials are conducted. We briefly discuss these trials, and demonstrate the large cost savings to the South African HIV programme if these are successful.
Databáze: Directory of Open Access Journals