Co-option of neurotransmitter signaling for inter-organismal communication in C. elegans

Autor: Christopher D. Chute, Elizabeth M. DiLoreto, Ying K. Zhang, Douglas K. Reilly, Diego Rayes, Veronica L. Coyle, Hee June Choi, Mark J. Alkema, Frank C. Schroeder, Jagan Srinivasan
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-11240-7
Popis: Inter-organismal signaling is essential for animals to navigate and survive in their natural environment, yet is unclear how these chemical communication channels may have evolved. Here, authors show that TYRA-2, an endogenous tyramine/octopamine receptor, is required for the chemosensation of an octopamine-derived pheromone and that this signaling system represents an inter-organismal communication channel that evolved via co-option of a neurotransmitter and its cognate receptor
Databáze: Directory of Open Access Journals