Challenge and Development Strategy for Colon-Targeted Drug Delivery System

Autor:	Raditya Iswandana, Kurnia Sari Setio Putri, Fathia Amalia Putri, Maxius Gunawan, Sekar Arum Larasati
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	colon-targeted drug delivery system colon disease polymer Pharmacy and materia medica RS1-441 Therapeutics. Pharmacology RM1-950
Zdroj:	Pharmaceutical Sciences and Research, Vol 9, Iss 1, Pp 17-27 (2022)
Druh dokumentu:	article
ISSN:	2407-2354 2477-0612
DOI:	10.7454/psr.v9i1.1251
Popis:	Colon-Targeted Drug Delivery System (CTDDS) is able to improve local therapeutic effects in the treatment of colon-specific diseases, such as Crohn’s disease, Ulcerative Colitis (UC), and Irritable Bowel Syndrome (IBS). A colon can also be a suitable site for systemic delivery of drugs susceptible to extreme gastric pH, such as peptides and protein therapeutics. The physiological conditions of the gastrointestinal tract and the physicochemical properties of drugs are being considered to develop strategies and approaches to overcome emerging challenges. This review will discuss factors, challenges, strategies, and approaches to developing a colon-targeted drug delivery system.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/d74ed26ef85b4221a04bc50d064ae68b Zobrazit plný text záznamu View record in DOAJ