Effectiveness of lotilaner on furuncular myiasis in dogs naturally infested with Dermatobia hominis (Diptera: Cuterebridae)

Autor: Rafaella Tortoriello, Luisa Xavier Christ, Victoria Caroline de Almeida Marques, Bruna Sampaio Martins, Julio Israel Fernandes
Jazyk: English<br />Spanish; Castilian<br />Portuguese
Rok vydání: 2024
Předmět:
Zdroj: Revista Brasileira de Parasitologia Veterinária, Vol 33, Iss 3 (2024)
Druh dokumentu: article
ISSN: 1984-2961
DOI: 10.1590/s1984-29612024054
Popis: Abstract An evaluation was made of the larvicidal efficacy of lotilaner (Credeli®) in the treatment of dogs naturally infested with Dermatobia hominis larvae. A total of 12 dogs presenting at least three live D. hominis larvae were medicated. The animals were medicated orally with a single dose of no less than 20 mg/kg lotilaner. After drug administration, the animals remained at their homes, and observations were made to verify the larvicidal effect 6 hours after treatment. Live larvae were considered any parasite that exhibited motility after removal. For each animal was using the formula: 100 x [(total of live larvae before treatment − total live larvae after treatment) /total of live larvae before treatment] as criteria for evaluating lotilaner efficacy. A total of 98 larvae were counted in 12 dogs, with an average of 8.1 larvae per animal. The effectiveness of lotilaner was 80.6%. Nineteen larvae were found alive, albeit presenting hypomobility and lethargic behavior. However, note that the evaluation was performed just six hours after administration of the drug. Lotilaner administered orally in a single dose of 20 mg/kg showed 80.6% efficacy six hours after treating dogs naturally infested with D. hominis.
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