Respiratory support effect on pharyngeal area in patients with amyotrophic lateral sclerosis: A fluoroscopic comparison of NIV, helmet/CPAP, and high-flow nasal cannula

Autor: Alessandra Dorça, José Vergara, Stacey A. Skoretz, Michael J. Brenner, Denise Sisterolli Diniz, Jorge L. Zeredo, Max Sarmet
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 46, Iss , Pp 101958- (2023)
Druh dokumentu: article
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2023.101958
Popis: The global use of noninvasive respiratory support provided by different supportive ventilation delivery methods (SVDMs) has increased, but the impact of these devices on the upper airway structures of patients with amyotrophic lateral sclerosis (ALS) is not known. We aimed to compare the pharyngeal cross-sectional area during spontaneous breathing with four different SVDMs: intranasal masks, oronasal masks, high-flow nasal cannula (HFNC), and helmet in patients with ALS. We compared measures of the pharyngeal area during spontaneous breathing and SVDM use. The greatest increase was observed with intranasal mask use, followed by HFNC, oronasal mask, and helmet respectively. In conclusion, upper airway opening in patients with ALS is enhanced by positive pressure with intranasal masks and HFNC, showing promise for increasing pharyngeal patency. Future studies should explore its applicability and effectiveness in maintaining long-term pharyngeal patency, especially in this population with bulbar weakness.
Databáze: Directory of Open Access Journals