Where will pediatric praziquantel be needed in Tanzania? Geographical variation in prevalence, and risk factors of Schistosoma mansoni in pre-school aged children in southern and north-western Tanzania

Autor: Humphrey D. Mazigo, Emmanuela E. Ambrose, Upendo J. Mwingira
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Parasite Epidemiology and Control, Vol 24, Iss , Pp e00337- (2024)
Druh dokumentu: article
ISSN: 2405-6731
DOI: 10.1016/j.parepi.2024.e00337
Popis: Background: Pediatric schistosomiasis has been recognized as a public health concern in schistosomiasis endemic areas of sub-Saharan Africa, including Tanzania. However, there is limited epidemiological information relating to pediatric schistosomiasis in Tanzania. Therefore, this current focused on assessing the geographical prevalence of S. mansoni infection and its associated risk factors in pre-school children (PreSAC) in southern and north-western Tanzania. Methods: A total of 1585 PreSAC aged 1–6 years were enrolled in a cross-sectional study. A single urine and stool sample were obtained from each child and processed using point-of-care circulating cathodic (POC-CCA) antigen and Kato Katz (KK) technique. The overall prevalence of S. mansoni infection based on KK technique and POC-CCA test were 18.6% (95%CI:16.7–20.6) and 28.3% (95%CI:26.1–30.6), respectively. The overall geometrical mean eggs per gram of faeces was 110.38epg (95% CI:97.3–125.3). The age group 4–6 years had the highest prevalence (P
Databáze: Directory of Open Access Journals
Externí odkaz: