Role of N-terminal pro-B-type natriuretic peptide in predicting mortality in heart failure

Autor: Kamal Kant Jena, N Vishwanathan, G Manohar, Prashant Kumar Singh, Nayan Chakraborty
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Clinical and Preventive Cardiology, Vol 10, Iss 2, Pp 63-67 (2021)
Druh dokumentu: article
ISSN: 2250-3528
DOI: 10.4103/jcpc.jcpc_65_20
Popis: Background: N-terminal pro-B-type natriuretic peptide (NT-proBNP) improves emergency room diagnosis and is a prognostic marker of acutely decompensated heart failure (HF) after hospitalization. We tried to assess the prognosis in heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF) using the biomarker. Methods: Patients were categorized into HFpEF (left ventricular ejection fraction [LVEF] ≥50%) (n = 102), HF with midrange EF (LVEF of 40%–49%) (n = 106), and HFrEF (LVEF ≤40%) (n = 112) as per the ESC classification of HF subtypes. Prognosis by absolute and percentage change in NT-proBNP at admission and at the 10th day of treatment was found in 3-month follow-up. Mortality after discharge was also assessed. Results: Among all HF groups, a reduction of NT-proBNP
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