Glioblastoma Multiforme in the over 70's: 'To treat or not to treat with radiotherapy?'

Autor: Aisling M. Glynn, Guhan Rangaswamy, Julianne O'Shea, Mary Dunne, Roger Grogan, Stephen MacNally, David Fitzpatrick, Clare Faul
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Cancer Medicine, Vol 8, Iss 10, Pp 4669-4677 (2019)
Druh dokumentu: article
ISSN: 2045-7634
40855848
DOI: 10.1002/cam4.2398
Popis: Abstract Background The incidence of Glioblastoma Multiforme (GBM) is increasing among the older population and is associated with poor prognosis. Management guidelines are lacking in this group. The purpose of this study was to analyze survival data and determine predictors of survival in patients aged ≥70 years treated with radiotherapy (RT) and/or Temozolomide. Materials and Methods A retrospective analysis of all GBM patients treated at our institution between January 2011 and January 2017 was carried out. Results One‐hundred and four patients were eligible. Median age was 73.8 years (70‐87). Thirty‐three patients received radical RT and 71 palliative RT. Overall median survival (MS) was 6 months. The MS was 10.6 months for radical patients and 4.9 months for palliative patients (P
Databáze: Directory of Open Access Journals
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