The subsequent risk of retinal vein occlusion disease after sinusitis diagnosis: a nationwide population-based study

Autor: Tsan-Yu Tsai, Jing-Yang Huang, Shih-Chun Chao, Shuo-Min Hsu, Shun-Fa Yang, Hung-Yu Lin
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-024-79765-6
Popis: Abstract Retinal vein occlusion (RVO) is a common retinal vascular disease that causes visual impairment. However, there is limited evidence regarding the relationship between sinusitis and risk of RVO. This study investigated the association between sinusitis and the subsequent risk of RVO disease. A retrospective cohort study was conducted and patients with sinusitis or RVO were selected from the National Health Insurance Research Database (NHIRD) of Taiwan. In this population-based study, we identified a total of 131,532 sinusitis patients, who were matched with 263,064 non-sinusitis individuals based on sex and age. The Cox proportional hazard regression was applied to demonstrate the adjusted hazard ratio (aHR) with 95% confidence interval (CI) of main outcomes. Our results showed that the crude hazard ratio (cHR) for the risk of RVO was 1.35 (95% CI: 1.20–1.52) in the sinusitis cohort compared with the non-sinusitis cohort. After adjustment for demographics and comorbidities in the multivariable cox regression, the adjusted hazard ratio (aHR) was 1.28 (95% CI: 1.13–1.44). Moreover, statistically significant differences were observed in the 14-year cumulative incidence of RVO (p
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje