Acute abdomen due to anaphylactic intestinal edema associated with systematic mastocytosis: a case report

Autor: Tomoko Takagishi, Katsuhiko Miki, Shinsaku Imashuku, Katsushige Takagishi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Emergency Medicine, Vol 15, Iss 1, Pp 1-5 (2022)
Druh dokumentu: article
ISSN: 1865-1372
1865-1380
DOI: 10.1186/s12245-022-00441-5
Popis: Abstract Background Among various anaphylactic conditions resulting in acute abdomen, mast cell activation disorders, although rare, are included in the differential diagnosis. Case presentation This report describes a 63-year-old Caucasian man who was brought to the emergency room with sudden onset abdominal pain, vomiting, and diarrhea, with breathing difficulty, and with facial swelling after quarrelling with an acquaintance. Computed tomography showed edematous and swollen intestines, consistent with splenomegaly. Physical findings included maculopapular cutaneous mastocytosis. He also had a long history of repeated episodes of anaphylaxis requiring occasional epinephrine auto-injector administration; however, the precise cause of anaphylaxis was previously undetermined. Blood tests showed high serum concentrations of soluble IL-2R and tryptase, suggesting mast cell-related disease. Subsequent biopsies of his bone marrow and cutaneous rash confirmed the diagnosis of systemic mastocytosis (SM). Conclusion SM was diagnosed in a patient with acute abdomen who visited the emergency room.
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje