Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity

Autor: Naiya B. Patel, Lorena A. Ostilla, Lyda Cuervo-Pardo, Sergejs Berdnikovs, Sergio E. Chiarella
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Clinical and Translational Allergy, Vol 9, Iss 1, Pp 1-3 (2019)
Druh dokumentu: article
ISSN: 2045-7022
DOI: 10.1186/s13601-019-0280-9
Popis: Abstract In two independent microarray studies involving primary airway epithelial cells, the relative gene expression of TMEM178 decreases with the progression of asthma severity. Our manuscript creates a paradigm for future studies dissecting the role of Tmem178 in the pathogenesis of severe asthma.
Databáze: Directory of Open Access Journals
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