| Autor: |
S. Jone Kirubavathy, R. Velmurugan, K. Parameswari, S. Chitra |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Arabian Journal of Chemistry, Vol 12, Iss 7, Pp 1581-1586 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1878-5352 |
| DOI: |
10.1016/j.arabjc.2014.10.013 |
| Popis: |
The complex tris(ethylenediamine)cobalt(III)chloride oxalate trihydrate [Co(en)3]Cl(C2O4)·3H2O crystallizes in the monoclinic space group C2/c with the following unit cell parameters a = 19.9318 (13), b = 9.3344 (4), c = 19.0881 (13) Å β = 96.846(3)°, Z = 8. The crystal structure was solved by direct methods and refined by full matrix least squares procedures to a final R value of 0.0314 for 4330 observed reflections. The reported cobalt complex is six co-ordinated through amine nitrogen with distorted octahedral geometry. There are uncoordinated chloride and oxalate ions along with the water molecules. In-vitro antimicrobial activity was studied against various test organisms and found to be good. From in-vitro cytotoxic activity of the synthesized complex, the IC50 value was found to be 55.85 μg/ml. Keywords: Cobalt complex, In-vitro antimicrobial activity, In-vitro cytotoxicity, Ethylene diamine |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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