Hypomagnesemia in persons with type 1 diabetes: associations with clinical parameters and oxidative stress

Autor: Peter R. van Dijk, F. Waanders, Jiedong Qiu, Hannah H. R. de Boer, H. van Goor, H. J. G. Bilo
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Therapeutic Advances in Endocrinology and Metabolism, Vol 11 (2020)
Druh dokumentu: article
ISSN: 2042-0196
20420188
DOI: 10.1177/2042018820980240
Popis: Background: Among persons with type 1 diabetes mellitus (T1DM) low concentrations of magnesium have been reported. Previous (small) studies also suggested a relation of hypomagnesemia with (poor) glycaemic control and complications. We aimed to investigate the magnitude of hypomagnesemia and the associations between magnesium with parameters of routine T1DM care in a population of unselected outpatients. Methods: As part of a prospective cohort study, initially designed to measure quality of life and oxidative stress, data from 207 patients with a mean age of 45 [standard deviation (SD) 12] years, 58% male, diabetes duration 22 [interquartile range (IQR) 16, 31] years and glycated haemoglobin (HbA1c) of 60 (SD 11) mmol/mol [7.6 (SD 1.0)%] were examined. Hypomagnesemia was defined as a concentration below
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